Glucose Monitoring Metrics

A deep dive into continuous glucose monitoring (CGM) and its impact on health optimization, particularly focusing on how blood glucose affects overall health and longevity.

Key CGM Concepts

  • Blood glucose spikes can damage organs over time
  • High glucose levels impact artery walls
  • Sustained high glucose leads to insulin resistance
  • Two key metrics to track:
    • Height of glucose spikes
    • Area under the curve (how long glucose stays elevated)

CGM Technology Landscape

  • Dexcom's Stello

    • First FDA-approved over-the-counter CGM
    • Released August 2023
    • Costs about $50 for 2 weeks of monitoring
  • Levels

    • Existing player in consumer CGM space
    • Requires prescription currently

Business Opportunities

  • Social/Community Platforms

    • Potential for "Strava for CGM" using Dexcom's API
    • Focus on sharing insights and competing on metrics
    • Example: Glucose Goddess (5M Instagram followers)
      • Charges $5/month for recipe club
      • Recently launched "Anti-spike" product
      • Gets 100k+ monthly website views
  • Education/Content

    • High demand for understanding glucose data
    • People want to know:
      • What constitutes a concerning spike
      • Meaning of double humps in readings
      • Impact of next-day glucose levels
      • Proper ranges and targets

Consumer Impact

  • Reveals hidden health issues

    • Thin people can have poor metabolic health
    • Shows impact of seemingly healthy foods
    • Exposes effects of different meal timing/combinations
  • Creates accountability

    • Can't hide from the data
    • Provides immediate feedback on food choices
    • Shows impact of lifestyle decisions
34:13 - 35:13
Full video: 59:35
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Steph Smith

Steph Smith is the host of the a16z podcast, focused on highlighting the most important trends within technology. Before joining Andreessen Horowitz, Steph led HubSpot's Creator Program, including their growing Podcast Network. She was also a writer for the Hustle.

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