Independent Replication Validates Science

Balaji argues that independent replication, not peer review, is the true foundation of scientific validation. He presents a framework for how math and computational verification can create more trustworthy science.

Core Concept: Independent Replication vs Peer Review

  • Science is based on independent replication, not peer review
  • Peer review is only a proxy for independent replication
  • Most peer reviews today are just emailed comments rather than actual experimental verification
  • True validation comes from being able to download and run code/experiments yourself

The Problem with Current Science

  • Science has become the basis of civilization, replacing religion
  • Scientific premises drive policy decisions (emissions, masks, etc.)
  • Current system relies too heavily on institutional authority
  • Trust has been eroded by incidents like the "noble lie" about masks during pandemic
  • Many studies have 0 replications but are treated same as well-proven theories

Math as Superior to Science

  • Math allows for verification without specialized equipment
  • Everyone has computers, enabling mathematical verification
  • Example: Bitcoin/crypto defeated traditional economic theories through mathematical proof
  • Mathematical verification is more accessible than scientific replication
  • Crypto shows how mathematical consensus can work at scale
    • Transaction confirmations are like independent replications
    • Multiple miners verify each transaction mathematically

Future Framework: Science on the Blockchain

  • Scientific papers could be fully reproducible from underlying data and code
  • All calculations could be independently verified
  • Papers could be compared against each other in common formats
  • Citations could be traced and verified through blockchain
  • Benefits:
    • Makes science more checkable and cumulative
    • Reduces reliance on central authorities
    • Creates universal format for scientific communication
    • Enables verification of calculations and premises
    • Makes citation trails traceable and verifiable

Key Distinction in Scientific Validity

  • True science has trillions of independent replications (like Maxwell's equations)
  • Modern studies often have zero replications
  • Number of independent replications, not citations, should be the measure of validity
  • Engineering success proves scientific validity through practical replication
02:11:15 - 02:15:38
Full video: 02:36:35
BS

Balaji Srinivasan

Former CTO of Coinbase and co-founder of genetic-consulting company Counsyl Inc. Holds a Ph.D. in Electrical Engineering from Stanford University.

Investor and author with expertise in biotech, computational genomics, and blockchain technology. Published "The Network State: How to Start a New Country" in 2022.

Advocates for cryptocurrency and technocapitalism, currently establishing The Network School near Singapore.

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